DBCO-Acid is widely utilized in bioconjugation and click chemistry applications due to its high reactivity with azides. It is commonly employed in the labeling and modification of biomolecules such as proteins, peptides, and nucleic acids, enabling precise and efficient attachment of functional groups or probes. In drug delivery systems, it facilitates the targeted conjugation of therapeutic agents to carriers, enhancing specificity and efficacy. Additionally, it plays a critical role in the development of bioimaging tools, allowing for the attachment of fluorescent or radioactive tags to track biological processes in real-time. Its use in material science includes the functionalization of surfaces and nanoparticles for advanced research and industrial applications.