Used as a key reagent in click chemistry, particularly in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling efficient bioconjugation for labeling biomolecules such as proteins and nucleic acids. Its alkyne and activated iodide groups allow dual functionality—facilitating crosslinking or immobilization on surfaces and tags in diagnostic probes. Commonly applied in pharmaceutical research for developing targeted drug delivery systems and in proteomics for activity-based protein profiling. Stable under standard handling conditions, it supports high-yield transformations in aqueous and organic media.