TAMRA-PEG4-alkyne is widely used in bioorthogonal chemistry for labeling biomolecules. Its alkyne group allows for efficient click chemistry reactions, particularly with azide-functionalized compounds, enabling the visualization and tracking of biomolecules in live cells and tissues. The TAMRA fluorophore provides strong red fluorescence, making it suitable for fluorescence microscopy and imaging applications. Additionally, the PEG4 spacer enhances solubility and reduces steric hindrance, improving the efficiency of conjugation reactions. This compound is commonly employed in proteomics, drug discovery, and cellular imaging studies to investigate molecular interactions and dynamics.