Propargyl-PEG4-beta-D-glucose is widely used in bioconjugation and chemical biology research. It serves as a versatile linker for attaching biomolecules, such as proteins, peptides, or antibodies, to other functional groups or surfaces. The propargyl group enables click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), which is highly efficient and selective. This makes it valuable for creating targeted drug delivery systems, diagnostic probes, and imaging agents. Additionally, its PEG4 spacer enhances solubility and reduces steric hindrance, improving the performance of the conjugated molecules in biological systems. This compound is also utilized in glycobiology studies to modify or label carbohydrates for investigating their roles in cellular processes.