NH-bis(PEG2-propargyl) is widely used in bioconjugation and click chemistry applications. Its propargyl groups enable efficient reactions with azides via copper-catalyzed azide-alkyne cycloaddition (CuAAC), making it valuable for labeling biomolecules such as proteins, peptides, and nucleic acids. The PEG (polyethylene glycol) spacers enhance solubility and reduce steric hindrance, improving reaction efficiency. This compound is particularly useful in drug delivery systems, where it facilitates the attachment of therapeutic agents to carriers or targeting molecules. Additionally, it is employed in material science for surface functionalization and the development of biofunctionalized polymers or nanoparticles. Its versatility makes it a key tool in research and industrial applications requiring precise molecular modifications.