Used extensively in bioconjugation and click chemistry applications, it serves as a linker to attach polyethylene glycol (PEG) chains to biomolecules, enhancing their solubility, stability, and bioavailability. Commonly applied in drug delivery systems, it helps improve the pharmacokinetics of therapeutic agents. Additionally, it plays a role in surface modification of nanoparticles and materials for biomedical research. Its alkyne group enables efficient coupling with azide-containing molecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC), making it valuable in labeling and tracking studies.