Used in organic synthesis as an alkylating agent, particularly in the preparation of heterocyclic compounds and pharmaceutical intermediates. Its iodo and alkyne functional groups allow for participation in cross-coupling reactions, such as Sonogashira coupling, enabling the construction of complex molecular frameworks. Commonly employed in the development of bioactive molecules and functionalized amides. Also utilized in click chemistry applications due to the presence of the terminal alkyne, facilitating rapid and selective reactions with azides to form triazole derivatives. Additionally, it can serve as a linker in biomolecular chemistry and in surface modification for surface chemistry and nanomaterials to enable specific binding capabilities.