Used primarily as an anticancer agent, particularly in the treatment of solid tumors. It functions as a hypoxia-activated prodrug, meaning it becomes active in low-oxygen environments commonly found in tumor tissues. This selective activation allows targeted delivery of cytotoxic effects to hypoxic cancer cells, minimizing damage to normal, well-oxygenated tissues. It has been investigated in clinical trials for cancers such as pancreatic, lung, and head and neck carcinomas, often in combination with other chemotherapeutic agents or radiation therapy to enhance overall antitumor efficacy.