1-Iodo-2-methylpropane is commonly used as an alkylating agent in organic synthesis, where it introduces the isobutyl group into various molecules. It is particularly useful in the preparation of pharmaceuticals and agrochemicals, as it facilitates the formation of carbon-carbon bonds. Additionally, it serves as a reagent in the synthesis of complex organic compounds, including natural products and fine chemicals. Its application extends to the field of material science, where it is used in the modification of polymers and surfaces to impart specific properties. In research laboratories, it is often employed in nucleophilic substitution reactions to study reaction mechanisms and kinetics.