1-Iodooctadecane is primarily used in organic synthesis as a long-chain alkylating agent. It is commonly employed in the preparation of surfactants, lubricants, and other specialty chemicals. The compound is also utilized in the synthesis of organic intermediates, particularly in the creation of quaternary ammonium compounds, which are widely used in fabric softeners, disinfectants, and phase transfer catalysts. Additionally, 1-Iodooctadecane finds application in research and development for modifying surfaces to impart hydrophobic properties, making it valuable in materials science and nanotechnology. Its role in the production of lipid-based drug delivery systems is also noteworthy, as it aids in the formulation of liposomes and other nanostructures for targeted drug delivery.