Reticuline is a key intermediate in the biosynthesis of numerous benzylisoquinoline alkaloids, making it valuable in the pharmaceutical industry for the production of important medicinal compounds. It serves as a precursor in the synthesis of opioids such as morphine and codeine, which are used for pain relief. It is also involved in the formation of berberine and tetrahydroberberine, compounds with antimicrobial and anti-inflammatory properties. Due to its role in plant metabolic pathways, reticuline is studied extensively in metabolic engineering and synthetic biology to develop microbial systems for sustainable production of high-value alkaloids. Additionally, it has been investigated for its potential neuroprotective and cardiovascular effects, including smooth muscle relaxation and possible use in treating neurological disorders.