Lappaconitine
98%(HPLC)
Reagent
Code: #202336
CAS Number
32854-75-4
blur_circular Chemical Specifications
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Molecular Information
Weight
584.7 g/mol
Formula
C₃₂H₄₄N₂O₈
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Storage & Handling
Storage
2-8ºC
description Product Description
Used as a non-opioid analgesic in clinical practice, particularly in Russia and some Asian countries, for the management of moderate to severe pain including postoperative and neuralgic pain. Its mechanism involves blocking voltage-gated sodium channels, which stabilizes neuronal membranes and reduces pain signal transmission. Due to its potent analgesic properties and lower risk of respiratory depression compared to opioids, it is considered an alternative in pain therapy where opioid side effects are a concern. However, its use requires careful dosing due to potential cardiotoxic and neurotoxic effects. Also investigated for antiarrhythmic activity, though this remains experimental.
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