Used in traditional medicine for its psychoactive properties, particularly in religious and spiritual rituals. Acts as a mild monoamine oxidase inhibitor (MAOI), which can enhance the effects of certain neurotransmitters in the brain. Found in plant extracts like those from Peganum harmala, it is sometimes used to potentiate the activity of other psychoactive substances. Also investigated for potential neuroprotective and anti-inflammatory effects in preclinical studies. Limited modern pharmaceutical use due to low potency and availability of more effective alternatives.