Coptisine is widely used for its antimicrobial and anti-inflammatory properties, making it valuable in traditional and modern medicine. It shows strong activity against various bacteria and fungi, particularly in treating gastrointestinal infections. It is also studied for its potential in managing diabetes due to its ability to improve insulin sensitivity and regulate blood glucose levels. In addition, coptisine exhibits anticancer effects by inhibiting the growth of certain tumor cells and inducing apoptosis. It has neuroprotective benefits and is being explored for use in neurodegenerative disorders like Alzheimer’s disease. Its antioxidant activity further supports its role in reducing oxidative stress in various disease conditions.