Used as a building block in organic synthesis, particularly in the preparation of cyclobutane-based pharmaceuticals and agrochemicals. Its nitrile groups allow for further functionalization, enabling the formation of carboxylic acids, amines, or heterocyclic compounds. The rigid trans-cyclobutane structure imparts stereochemical stability, making it valuable in the design of conformationally restricted molecules for drug discovery. Also employed in materials science to modify polymer backbone rigidity and thermal stability.