Trans-1,4-Diaminocyclohexane is widely used in the production of polymers and resins, particularly in the synthesis of polyamides and polyurethanes. Its rigid cyclohexane backbone contributes to the thermal stability and mechanical strength of these materials, making them suitable for high-performance applications such as automotive parts, coatings, and adhesives.

In the pharmaceutical industry, it serves as a building block for the synthesis of various drugs, including those targeting central nervous system disorders. Its structural properties allow it to act as a versatile intermediate in organic synthesis, enabling the creation of complex molecules with specific biological activities.

Additionally, it is employed in the preparation of corrosion inhibitors, where its amine groups help form protective layers on metal surfaces, preventing degradation in harsh environments. This makes it valuable in industries like oil and gas, where equipment longevity is critical.

In research, it is utilized as a ligand in coordination chemistry, aiding in the development of catalysts for chemical reactions. Its ability to form stable complexes with metal ions is leveraged in both industrial and academic settings for advancing catalytic processes.