1-((Trimethylsilyl)ethynyl)cyclopropane-1-carboxylic acid

98%

Reagent Code: #243248
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CAS Number 1268810-07-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 182.29 g/mol
Formula C₉H₁₄O₂Si
badge Registry Numbers
MDL Number MFCD20660917
inventory_2 Storage & Handling
Storage Room temperature, inert gas

description Product Description

Used as a key intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. Its alkyne functionality, protected by a trimethylsilyl group, allows for selective deprotection and coupling reactions, such as Sonogashira cross-coupling, enabling the construction of complex molecular architectures. The cyclopropane ring adds strain and rigidity, which can enhance binding selectivity in bioactive molecules. Commonly employed in medicinal chemistry for modifying lead compounds to improve metabolic stability and pharmacokinetic properties.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,990.00
inventory 250mg
10-20 days ฿3,270.00
inventory 1g
10-20 days ฿9,850.00
inventory 5g
10-20 days ฿43,380.00

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