Used as a key chiral intermediate in the synthesis of antifungal agents, particularly in the production of triazole antifungals such as efinaconazole and related derivatives. Its cyclopropane structure with specific stereochemistry enhances binding affinity to fungal cytochrome P450 enzymes, improving selectivity and potency. The difluorophenyl group contributes to metabolic stability and lipophilicity, which aids in tissue penetration and oral bioavailability. Commonly employed in pharmaceutical research and development for optimizing antifungal drug candidates.