Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of biologically active compounds targeting central nervous system disorders and anti-inflammatory agents. Its rigid cyclobutane backbone and polar functional groups make it valuable for modulating molecular conformation and improving metabolic stability in drug candidates. Frequently employed in medicinal chemistry to enhance binding selectivity and potency in enzyme inhibitors. Also utilized in the preparation of fluorinated building blocks for agrochemicals and specialty materials due to the influence of the trifluoromethyl group on lipophilicity and bioavailability.