Used as a key building block in medicinal chemistry, particularly in the synthesis of bioisosteres for benzene and other aromatic rings. Its strained bicyclic structure enables the replacement of flat, aromatic systems with three-dimensional aliphatic cores, improving solubility, metabolic stability, and success in drug discovery. Commonly employed in the development of CNS agents, kinase inhibitors, and PET tracers due to its ability to present functional groups in a unique spatial orientation. The bromomethyl group allows for easy derivatization via nucleophilic substitution or cross-coupling reactions, making it valuable for late-stage functionalization in pharmaceutical research.