3-(tert-Butyldimethylsilyloxy)propan-1-amine
98%
Reagent
Code: #147771
CAS Number
115306-75-7
blur_circular Chemical Specifications
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Molecular Information
Weight
189.37 g/mol
Formula
C₉H₂₃NOSi
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Registry Numbers
MDL Number
MFCD18206137
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Physical Properties
Boiling Point
70°C/3.5mmHg(lit.)
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Storage & Handling
Density
0.849±0.06 g/cm3(Predicted)
Storage
Room temperature, stored in inert gas
description Product Description
Used as an intermediate in organic synthesis featuring a free primary amine and a tert-butyldimethylsilyloxy (TBS) protected hydroxyl group at the 3-position of the propyl chain, particularly in the pharmaceutical and agrochemical industries. The silyl ether provides stability under various reaction conditions, including reductions, oxidations, and coupling reactions, while allowing selective deprotection of the hydroxyl when needed. This structure is valuable in multi-step syntheses for introducing the 3-aminopropyl functionality with precise control over the hydroxyl group, enabling the construction of complex molecules without interference from the alcohol.
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