Used as a key building block in medicinal chemistry, particularly in the design of bioisosteres for meta-substituted arenes. Its rigid, three-dimensional structure helps improve pharmacokinetic properties such as metabolic stability and solubility in drug candidates. Commonly employed in the development of CNS-active compounds and other pharmaceuticals where reduced aromatic ring content is desired. Also utilized in agrochemicals and materials science for introducing strain and polarity into molecular frameworks.