4-tert-Butyldimethylsiloxy-1-butanol
>97%
Reagent
Code: #144889
CAS Number
87184-99-4
blur_circular Chemical Specifications
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Molecular Information
Weight
204.38 g/mol
Formula
C₁₀H₂₄O₂Si
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Registry Numbers
MDL Number
MFCD04974070
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Physical Properties
Boiling Point
63-66ºC0.3 mm Hg(lit.)
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Storage & Handling
Density
0.888 g/mL at 25ºC(lit.)
Storage
Room temperature, dry
description Product Description
Used as a protected form of 1,4-butanediol in organic synthesis, particularly in the pharmaceutical and fine chemical industries. The tert-butyldimethylsiloxy (TBS) group acts as a protecting group for the hydroxyl function, allowing selective reactions at the other end of the molecule. This compound is valuable in multi-step syntheses where controlled deprotection and functional group manipulation are required. It is commonly employed in the preparation of complex molecules such as natural products and active pharmaceutical ingredients (APIs), where stability and chemoselectivity are critical. Its use enables efficient route design in both research and industrial settings.
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