Acetyl bromide is primarily used as an acetylating agent in organic synthesis. It efficiently introduces acetyl groups into various substrates, especially in the modification of aromatic compounds, alcohols, and amines. Due to its high reactivity, it is favored in laboratory-scale reactions where rapid acetylation is required. It is also employed in the preparation of other acetyl derivatives and intermediates used in pharmaceuticals, dyes, and agrochemicals. Its use is typically limited to controlled environments because of its moisture sensitivity and corrosive nature.