CVT-10216 is primarily used in research settings as a selective inhibitor of aldehyde dehydrogenase 2 (ALDH2). Its application is significant in studying the role of ALDH2 in various physiological and pathological processes, particularly in conditions related to oxidative stress and alcohol metabolism. Researchers utilize CVT-10216 to explore its potential in mitigating the effects of alcohol-induced toxicity and cardiovascular diseases. Additionally, it serves as a tool compound in understanding the mechanisms underlying diseases where ALDH2 dysfunction plays a role, such as certain types of cancer and neurodegenerative disorders. Its use in preclinical studies helps in identifying therapeutic targets and developing novel treatments for ALDH2-related conditions.