This chemical is primarily used as a reagent in organic synthesis to introduce a protected 2-hydroxyethyl group onto alcohols via nucleophilic substitution of the bromo moiety. The reaction forms RO-CH₂-CH₂-O-Si(CH₃)₂C(CH₃)₃ (where R is the alcohol residue), with the tert-butyldimethylsilyl (TBDMS) group protecting the terminal hydroxyl during multi-step reactions, ensuring it remains unaffected by subsequent transformations. The TBDMS protecting group can be selectively removed under mild conditions, such as treatment with tetrabutylammonium fluoride (TBAF), to reveal the free hydroxyl group. The bromoethoxy moiety enables further functionalization through alkylation. It is commonly applied in the synthesis of complex molecules, such as pharmaceuticals, natural products, and polymers, where selective protection and deprotection of functional groups are critical. Its stability under various reaction conditions makes it a valuable tool in synthetic chemistry.