This chemical is primarily used in organic synthesis as a protecting group for alcohols, particularly in the preparation of complex molecules such as pharmaceuticals and natural products. The tert-butyldiphenylsilyl (TBDPS) group is stable under various reaction conditions, making it suitable for multi-step synthesis. It is often employed to selectively protect hydroxyl groups, allowing chemists to perform reactions on other functional sites without interference. After the desired transformations are complete, the TBDPS group can be removed under mild conditions, restoring the original alcohol functionality. This compound is particularly valuable in the synthesis of nucleosides, carbohydrates, and other biologically active molecules. Its application ensures high yields and efficient processes in the development of therapeutic agents and other advanced materials.