methyl 5-((tert-butyldimethylsilyl)oxy)-2-methylbenzoate
98%
Reagent
Code: #209289
CAS Number
866028-37-7
blur_circular Chemical Specifications
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Molecular Information
Weight
280.44 g/mol
Formula
C₁₅H₂₄O₃Si
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Storage & Handling
Storage
2-8℃
description Product Description
Used as a key intermediate in organic synthesis, particularly in the construction of complex molecules such as natural products and pharmaceuticals. Its primary application lies in protecting the phenolic hydroxyl group during multi-step syntheses, allowing selective reactions at other sites in the molecule. The tert-butyldimethylsilyl (TBS) group provides robust protection under a variety of reaction conditions, while the methyl ester offers a handle for further transformations, such as hydrolysis, reduction, or cross-coupling reactions. Commonly employed in the synthesis of bioactive compounds where regioselectivity and functional group compatibility are critical.
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