Prealbumin, derived from human plasma, is widely utilized in medical diagnostics and research due to its role as a biomarker for various health conditions. It is particularly significant in assessing nutritional status, as low levels often indicate malnutrition, especially in elderly patients or those with chronic illnesses. Additionally, prealbumin is used to monitor the effectiveness of nutritional interventions and recovery in hospitalized individuals. In clinical settings, it serves as a sensitive indicator of liver function and thyroid health, as it is involved in the transport of thyroid hormones and vitamin A. Furthermore, prealbumin levels are measured to evaluate inflammation and acute-phase responses in conditions such as infections, trauma, or autoimmune diseases. Its stability and short half-life make it a reliable marker for rapid changes in a patient's health status.