ITE analog (ITK) is primarily utilized in research focused on immune modulation and inflammation. It acts as an agonist for the aryl hydrocarbon receptor (AhR), which plays a significant role in regulating immune responses. Researchers use ITE analogs to study the effects of AhR activation on T-cell differentiation, particularly in the context of autoimmune diseases and cancer immunotherapy. By modulating AhR signaling, ITE analogs can influence the balance between pro-inflammatory and anti-inflammatory responses, making them valuable tools for understanding immune system regulation. Additionally, these compounds are explored for their potential therapeutic applications in conditions like multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease, where immune dysregulation is a key factor.