(E)-4-Fluorobenzaldehyde oxime is primarily used in organic synthesis as an intermediate for the production of various pharmaceuticals and agrochemicals. It serves as a key building block in the development of compounds with potential biological activities, such as antifungal, antibacterial, and anti-inflammatory agents. Additionally, it is utilized in the synthesis of Schiff bases, which are important in coordination chemistry and material science. Its fluorinated structure enhances the stability and reactivity of derived compounds, making it valuable in research and industrial applications.