(2,5-Dichlorophenyl)methanesulfonyl chloride is primarily used as a key intermediate in organic synthesis, particularly in the preparation of sulfonamide derivatives. These derivatives are widely utilized in the pharmaceutical industry for the development of various drugs, including antibiotics, anti-inflammatory agents, and other therapeutic compounds. The compound's reactive sulfonyl chloride group allows it to easily form bonds with amines, enabling the creation of sulfonamides, which are critical in medicinal chemistry. Additionally, it finds applications in agrochemical research for the synthesis of herbicides and pesticides, where its structural properties contribute to the development of effective crop protection agents. Its role in chemical research also extends to the synthesis of complex organic molecules for material science and industrial applications.