Used in biopharmaceutical manufacturing for the purification of monoclonal antibodies and other immunoglobulins. Its main application is in affinity chromatography, where it selectively binds the Fc region of antibodies, allowing impurities to be washed away. After binding, the purified antibodies are eluted under mild acidic conditions. This resin is especially valuable in large-scale antibody production due to its high binding capacity, specificity, and reusability. It supports high-throughput processes in research, quality control, and therapeutic protein development.