ABT-702 dihydrochloride
10mM in DMSO
Reagent
Code: #133914
CAS Number
1188890-28-9
blur_circular Chemical Specifications
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Molecular Information
Weight
536.25 g/mol
Formula
C₂₂H₂₁BrCl₂N₆O
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Storage & Handling
Storage
-20°C, avoiding light
description Product Description
ABT-702 dihydrochloride is primarily used in scientific research as a potent and selective inhibitor of adenosine kinase, an enzyme involved in regulating adenosine levels in the body. By inhibiting this enzyme, ABT-702 increases extracellular adenosine concentrations, which can modulate neuronal activity and reduce inflammation. It is widely used in studies related to pain management, particularly neuropathic and inflammatory pain, due to adenosine’s role in pain signaling pathways. Researchers also explore its potential in neurological disorders such as epilepsy and neurodegenerative diseases, where adenosine has neuroprotective effects. Additionally, it serves as a pharmacological tool to investigate the adenosinergic system in cellular and animal models, helping to elucidate the therapeutic potential of targeting adenosine metabolism.
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