The chemical is widely used in bioconjugation and drug delivery systems. It serves as a linker molecule, enabling the attachment of therapeutic agents or targeting moieties to biomolecules like proteins, peptides, or antibodies. Its PEG (polyethylene glycol) spacer enhances solubility and reduces immunogenicity, while the PFP (pentafluorophenyl) ester group facilitates efficient and selective reactions with amines, making it valuable in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals. Additionally, it is employed in surface modification and functionalization of nanoparticles for improved biocompatibility and targeted delivery in nanomedicine applications.