5,8-Dioxa-2,11-diazadodecanoic acid, 12-[6-[2-(1-methylethylidene)hydrazinyl]-3-pyridinyl]-12-oxo-, (1alpha,8alpha,9alpha)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester

98%

Reagent Code: #167647
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CAS Number 1507370-54-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 499.61 g/mol
Formula C₂₆H₃₇N₅O₅
badge Registry Numbers
MDL Number MFCD34470199
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted cancer therapies. Its unique bridged bicyclic structure and hydrazine-pyridine functionality enable selective binding to kinase enzymes, making it valuable in developing inhibitors for tumor growth signaling pathways. The compound’s ester linkage allows for prodrug strategies, enhancing bioavailability in vivo. It is also explored in antibody-drug conjugates (ADCs) due to its stability and ability to be functionalized, facilitating precise delivery of cytotoxic agents to cancer cells. Additionally, its oxadiazole-like framework contributes to metabolic resistance, improving half-life in biological systems.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿69,250.00

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