5,8-Dioxa-2,11-diazadodecanoic acid, 12-[6-[2-(1-methylethylidene)hydrazinyl]-3-pyridinyl]-12-oxo-, (1alpha,8alpha,9alpha)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester
98%
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Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted cancer therapies. Its unique bridged bicyclic structure and hydrazine-pyridine functionality enable selective binding to kinase enzymes, making it valuable in developing inhibitors for tumor growth signaling pathways. The compound’s ester linkage allows for prodrug strategies, enhancing bioavailability in vivo. It is also explored in antibody-drug conjugates (ADCs) due to its stability and ability to be functionalized, facilitating precise delivery of cytotoxic agents to cancer cells. Additionally, its oxadiazole-like framework contributes to metabolic resistance, improving half-life in biological systems.
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