Used in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It acts as a cytotoxic payload that binds to tubulin, inhibiting microtubule formation, which disrupts cell division and leads to apoptosis in tumor cells. Due to its high potency, it is particularly effective when linked to monoclonal antibodies that deliver the compound selectively to cancer cells, minimizing damage to healthy tissues. Research focuses on its application in treating solid tumors and hematological malignancies.