tert-Butyl ((S)-5-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-phenylpropanamido)-6-((4-(hydroxymethyl)phenyl)amino)-6-oxohexyl)carbamate
98%
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description Product Description
Used in bioconjugation processes, particularly in the development of antibody-drug conjugates (ADCs). The chemical contains a protected amine group (Boc-protected) and a maleimide functionality, enabling site-specific coupling to thiol groups on proteins or antibodies. The linker region includes cleavable amide bonds and a benzyl alcohol group (from 4-(hydroxymethyl)phenyl), supporting design for controlled drug release in targeted therapies. Commonly applied in pharmaceutical research for delivering cytotoxic agents selectively to cancer cells, improving therapeutic efficacy while minimizing off-target effects. Its peptide-like structure with amide linkages provides stability in circulation and efficient intracellular drug release after internalization.
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