Used in pharmaceutical research as a biotin-based linker or functionalized intermediate in the development of targeted therapies, particularly in antibody-drug conjugates (ADCs). The biotin moiety in the imidazolone-thiophene core enables specific binding to streptavidin, facilitating targeted delivery. Its alkyne group enables click chemistry reactions, allowing efficient conjugation to azide-containing molecules. The polyether chain enhances solubility and flexibility, improving bioavailability and binding kinetics. Commonly employed in bioconjugation strategies for cancer therapeutics and diagnostic probes.