1-Adamantyl isothiocyanate is primarily used in organic synthesis as a versatile building block for the creation of more complex chemical structures. Its unique adamantane group provides steric bulk, which can influence the reactivity and stability of the resulting compounds. This chemical is often employed in the development of pharmaceuticals, particularly in the synthesis of compounds with potential biological activity, such as anticancer or antimicrobial agents. Additionally, it serves as a key intermediate in the preparation of advanced materials, including polymers and coatings, where its rigid structure can enhance thermal and mechanical properties. Its isothiocyanate group also makes it a valuable reagent in the modification of proteins and peptides, aiding in biochemical research and drug discovery.