Used as an activating agent in peptide synthesis, this compound facilitates the formation of amide bonds by enhancing the reactivity of carboxylic acids. It is particularly effective in solid-phase peptide synthesis where efficient coupling and minimal racemization are critical. Its pyridinyl disulfide group also allows for reversible conjugation, making it useful in the development of bioconjugates and protein labeling applications. Additionally, it serves in the preparation of active esters for crosslinking biomolecules in biochemical assays and pharmaceutical research.