Latrunculin A (LAT-A)
98%
Reagent
Code: #202368
CAS Number
76343-93-6
blur_circular Chemical Specifications
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Molecular Information
Weight
421.6 g/mol
Formula
C₂₂H₃₁NO₅S
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Storage & Handling
Storage
-20℃
description Product Description
Used primarily in cell biology research to disrupt actin polymerization. It binds to monomeric actin, preventing its incorporation into filaments, which leads to the breakdown of the actin cytoskeleton. This property makes it a valuable tool for studying actin-dependent cellular processes such as cell motility, cytokinesis, endocytosis, and membrane trafficking. Often applied in microscopy studies to visualize the role of actin dynamics in live cells. Also used in experiments to synchronize cell cycle stages or induce cell rounding for easier harvesting. Due to its ability to rapidly depolymerize actin, it is favored over other inhibitors like cytochalasin in certain experimental settings.
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