Hydroxylamine-O-sulfonic acid is widely used as a versatile reagent in organic synthesis. It serves as a strong oxidizing agent, particularly in the preparation of oximes from carbonyl compounds, which are valuable intermediates in the production of pharmaceuticals and agrochemicals. The compound is also employed in the synthesis of heterocycles, such as pyrazoles and isoxazoles, which are important in drug discovery. Additionally, it is utilized in the modification of nucleic acids and proteins for biochemical research, enabling the introduction of specific functional groups. Its ability to act as a nitrene precursor makes it useful in the formation of amines and other nitrogen-containing compounds. In industrial applications, it plays a role in the production of dyes, pigments, and other fine chemicals.