(/-)-1-METHOXY-1-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE
98%
science Other reagents with same CAS 64312-89-6
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This specialty chemical is an acyl chloride derivative of methoxy(trifluoromethyl)phenylacetic acid, commonly known as Mosher's acid chloride. It is primarily used as a chiral derivatizing agent in organic chemistry for the preparation of Mosher's esters, which enable the determination of enantiomeric purity and absolute configuration via NMR spectroscopy. This makes it invaluable in pharmaceutical research for analyzing chiral compounds and developing enantiomerically pure APIs. Additionally, its reactive acyl chloride group allows it to serve as a versatile building block in the synthesis of amides, esters, and other derivatives for more complex molecules in agrochemicals, where the trifluoromethyl group enhances biological activity and metabolic stability. It also finds applications in materials science for modifying polymers and creating functionalized coatings with tailored properties. As a key intermediate, its niche reactivity supports advanced research and industrial processes in stereochemistry and fine chemical synthesis.
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