The Boron Trifluoride-Butanol complex is a specialized reagent used primarily in organic synthesis as a milder, safer alternative to anhydrous BF₃. It serves as a catalyst for various reactions, including esterification, transesterification, polymerization, and alkylation processes. It is particularly effective in the production of resins, plastics, and biodiesel, where it enhances curing, hardening, and fatty acid esterification properties. Additionally, it is employed in the synthesis of pharmaceuticals and agrochemicals, facilitating the formation of complex molecules. As a Lewis acid, it promotes esterification and etherification reactions. In analytical chemistry, especially for fats and oils, it is utilized for derivatization of compounds to improve their detection and separation in chromatographic techniques such as GC-FID.