PF-06424439 methanesulfonate
10mM in DMSO
Reagent
Code: #224264
CAS Number
1469284-79-4
blur_circular Chemical Specifications
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Molecular Information
Weight
536.05 g/mol
Formula
C₂₃H₃₀ClN₇O₄S
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Storage & Handling
Storage
-20°C
description Product Description
Used in research for the treatment of obesity and type 2 diabetes, this compound acts as a potent and selective inhibitor of acetyl-CoA carboxylase (ACC), an enzyme involved in fatty acid metabolism. By inhibiting ACC, it helps reduce fat synthesis and increase fat oxidation, leading to improved metabolic health in preclinical models. It has shown potential in reducing liver fat, body weight, and insulin resistance, making it a candidate for development in metabolic disorder therapies. Studies are primarily at the experimental stage, focusing on pharmacokinetics and efficacy in animal models.
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