ND-646 is a potent and selective inhibitor of acetyl-CoA carboxylase (ACC), an enzyme crucial for fatty acid synthesis and oxidation. Its primary application lies in the field of cancer research, where it is used to study the role of ACC in tumor growth and metabolism. By inhibiting ACC, ND-646 disrupts fatty acid synthesis, which is essential for cancer cell proliferation, making it a valuable tool for understanding metabolic pathways in cancer biology. Additionally, it is explored in metabolic disorders, such as obesity and diabetes, to investigate the regulation of lipid metabolism and energy homeostasis. Researchers also utilize ND-646 to assess its potential as a therapeutic agent in diseases where abnormal lipid metabolism plays a key role.