MLN-4760 is primarily used in research settings as a potent and selective inhibitor of angiotensin-converting enzyme 2 (ACE2). Its application is significant in studying the role of ACE2 in various physiological and pathological processes, particularly in cardiovascular and renal systems. Researchers utilize MLN-4760 to explore ACE2's involvement in blood pressure regulation, heart function, and its interaction with the renin-angiotensin system. Additionally, it is employed in investigations related to viral infections, as ACE2 serves as a receptor for certain viruses, including SARS-CoV-2. By inhibiting ACE2, MLN-4760 helps scientists understand the mechanisms of viral entry and potential therapeutic targets. Its use is confined to laboratory studies and is not applied in clinical or therapeutic contexts.