Angiotensin converting enzyme inhibitors are primarily used in the treatment of high blood pressure (hypertension). They help relax blood vessels, allowing blood to flow more easily and reducing the workload on the heart. This makes them effective in managing conditions like heart failure and improving survival rates after heart attacks. They are also prescribed to protect kidney function in patients with diabetes or chronic kidney disease, as they reduce proteinuria and slow disease progression. Additionally, these inhibitors are sometimes used to prevent migraines and treat scleroderma-related kidney problems. Their ability to modulate the renin-angiotensin system makes them a cornerstone in cardiovascular and renal therapy.