N-(3-(1H-imidazol-1-yl)propyl)-1-(4-fluorophenyl)-2,2-dimethylcyclopropane-1-carboxamide

≥95%

Reagent Code: #215176
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CAS Number 1434927-54-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 315.3852 g/mol
Formula C₁₈H₂₂FN₃O
badge Registry Numbers
MDL Number MFCD25546261
thermostat Physical Properties
Boiling Point 536.1±50.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.18±0.1 g/cm3(Predicted)
Storage 2-8°C

description Product Description

This compound acts as an enzyme inhibitor related to inflammation, specifically demonstrating potential to inhibit 5-lipoxygenase (5-LO), which plays a crucial role in leukotriene production—substances that trigger inflammation in the body. As such, it holds promise for treating chronic inflammatory conditions, including asthma, rheumatoid arthritis, and atopic dermatitis.

Additionally, it exhibits anti-inflammatory activity in cellular and animal models, significantly reducing the production of pro-inflammatory cytokines such as TNF-α and IL-6. This positions it as an attractive candidate for developing novel therapeutics aimed at modulating immune responses in relevant diseases.

Preliminary research indicates low toxicity and acceptable safety profiles in animal studies, suggesting feasibility for progression to human clinical trials.

It is employed in the synthesis of pharmaceutical intermediates and in medicinal chemistry to optimize lead compounds for enhanced metabolic stability and binding affinity.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿32,000.00
inventory 25mg
10-20 days ฿64,000.00
inventory 50mg
10-20 days ฿112,000.00

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